Pain and inflammation are the most common disorders faced by the clicnian and physiotherapist in their day to day practice. Fulfilling the patient expectations o a RAPID and magical relief from pain is an uphill task that we face. There are several emerging therapeutic options to meet this challenge but we are still far off from the  EUTOPIA of the well tolerated MAGICAL pill. Yet we must look at the overall perspective of the currently available anti inflammatory drugs and painkillers so that we can make a well informed choice of the RIGHT drug for every patient. After more than 100 years since the advent of Aspirin , and thousands of studies on NSAIDs , it is now possible to find the answers to the dilemmas posed by NSAIDs to the practicing clinician .

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